| Anna Chancellor | Questular Rontok |
| Warwick Davis | Marvin the Paranoid Android |
| Mos Def | Ford Prefect |
| Zooey Deschanel | Tricia McMillan |
| Martin Freeman | Arthur Dent |
| Stephen Fry | The Book |
| Bill Bailey | Voice of the Whale |
| John Malkovich | Humma Kavula |
| Bill Nighy | Slartibartfast |
| Sam Rockwell | Zaphod Beeblebrox |
| Su Elliot | Pub Customer (as Su Eliott) |
| Richard Griffiths | Jeltz (voice) |
| Dominique Jackson | Fook |
| Simon Jones | |
| Thomas Lennon | |
| Helen Mirren |
| Director | Garth Jennings |
| Producer | Gary Barber; Roger Birnbaum |
| Writer | Douglas Adams; Karey Kirkpatrick |
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| Deleted Scenes - Bulldozed right out of the movie Fake Deleted Scenes - Way, way too-far-out outtakes Additional Guide Entry - What the Guide has to say about quite possibly the oddest thing in the universe Sing Along "So Long & Thank For All The Fish" - Performed by the second most intelligent creatures on Earth "The Making of The Hitchhiker's Guide To The Galaxy" 2 Wholly Remarkable Audio Commentaries - Executive Producer and Douglas Adams' Colleague Sean Salle; Producer & Actors Set-Top Game: Marvin's Hangman - A simple word game with detachable results using Marvin the paranoid android |